Clinical significance of breast-specific gamma imaging in diagnosis of breast cancer

doi:10.3877/cma. j. issn.1674-0807.2014.04.004

Abstract

Abstract:

Objective

To evaluate the clinical significance of breast-specific gamma imaging (BSGI)in diagnosis of breast cancer.

Methods

We performed a perspective study of 136 patients with indeterminate breast lesions who underwent dual-phase BSGI in our hospital from March 2012 to December 2013. All included lesions were confirmed by pathology. BSGI was evaluated based on the visual interpretation and dual-phase semi-quantitative indices of lesion to non-lesion (L/N) ratio, which were compared with pathological results.Difference of L/N ratio of BSGI between benign and malignant breast lesions was analyzed by Mann-Whitney U nonparametric test.

Results

The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of BSGI in the diagnosis of breast cancer were 95.1%(97/102), 73.5%(25/34), 89.7%(122/136), 91.5%(97/106) and 83.3%(25/30), respectively. L/N ratio of BSGI in breast cancer was significantly higher than that of benign tumor (2.98±1.29 vs 0.95±1.11, Z = -7.125, P = 0.000).

Conclusion

BSGI has a significant clinical value in the diagnosis of breast cancer.

Key words: Breast neoplasms, Diagnostic imaging

Weige Yang, Hongcheng Shi, Hui Tan, Hong Wang, Wei Zhu, Zi’ang Yang, Hongwei Zhang. Clinical significance of breast-specific gamma imaging in diagnosis of breast cancer[J]. Chinese Journal of Breast Disease(Electronic Edition), 2014, 08(04): 244-247.

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URL: https://zhrxbzz.cma-cmc.com.cn/EN/10.3877/cma. j. issn.1674-0807.2014.04.004

https://zhrxbzz.cma-cmc.com.cn/EN/Y2014/V08/I04/244

Figures/Tables 4

References 11

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